hrp0089p2-p301 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

Efficacy and Safety of Triptorelin 3-Month Formulationin Patients with Central Precocious Puberty and BMI Evaluation.

Galli Francesca , Cavarzere Paolo , Ben Sarah Dal , Antoniazzi Franco , Gaudino Rossella

Background: Different formulations of gonadotropin-releasing hormone agonist (GnRHa) are available for the treatment of central precocious puberty (CPP). Currently there are few data on quarterly formulation depot (11.25 mg) during treatment.Aim: The purpose of this study is to analyse the effect of Triptorelin 11.25 mg 3-months depot in comparison with the monthly 3.75 mg formulation at the beginning and during the treatment of CPP.<p class="abstext...

hrp0089p2-p331 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

The Impact of Central Precious Puberty on Health-relatedqualityoflifeand Social, Emotive and Behavioral Competences Among Children Treated with GnRHa

Galli Francesca , Cavarzere Paolo , Ben Sarah Dal , Antoniazzi Franco , Gaudino Rossella

Background: Central precocious puberty (CPP) may affect quality of life (QOL) due to premature body and psychological changes that characterize this pathology. Few data are available on health-related quality of life (HRQOL) and social, emotive and behavioral competences in CPP children treated with gonadotropin-releasing hormone agonists (GnRHa). This study aimed to investigate these aspects in a group of CPP girls during therapy.Methods: Fifty-four CPP...